THE MICRODETERMINATION OF GOLD IN BIOLOGICAL FLUIDS

Microdetermination of Chloride in Biological Fluids, with Solid Silver Iodate

was outlined in detail, with gasometric measurement of the iodate resulting from the reaction. In this paper titrimetric measurement of the iodate is described. Titrimetric measurement of the iodate is directly applicable to the supernatant fluid in the AgI08 precipitation of chloride from salt solutions, urine, serum, and protein-free jiltrate of serum and of whole blood.’ For the titrimetric ...

Estimation of Gold in Biological Fluids.

Chrysotherapy has now become a recognized form of treatment in rheumatoid arthritis and much experimental work has been done to determine the fate of gold salts in the body. Kling and his colleagues (1939) showed that gold compounds were deposited mainly in reticulo-endothelial cells, of which synovial membrane contains a large number. They were able to detect spectrographically the presence of...

The Micro-Determination of Gold in Biological Fluids and Tissues.

The increasing interest in the use of gold salts as chemotherapeutic agents in the treatment of certain diseases (Hartfall, et al., 1937) has made apparent the necessity of an accurate, specific, and sensitive method for the determination of gold in various biological materials. Moreover, the lack of information regarding the metabolism and pharmacology of this element further emphasizes this n...

Photoelectric Microdetermination of Chloride in Biological Fluids, and of Iodate and Iodine in Protein-free Solutions

The Microdetermination of Biological Copper with Oxalyldihydrazide.

Methods are described for the determination of microgram quantities of biological copper in aqueous medium as the intensely coloured oxalyldihydrazide-acetaldehyde complex (molar extinction coefficient 23,000 to 23,500). The methods are applicable on a routine basis to any biological material, in particular to serum, urine, or tissues, such as liver, brain, or kidney. In the case of urine a sim...